As Nigel approaches the end of his final term as Chair of the GPhC, he will reflect on how the GPhC has developed how it regulates in response to changes in pharmacy practice and the needs of patients and the public. Nigel will highlight major changes in the education and training of pharmacists and pharmacy technicians, the GPhC’s approach to inspections and enforcement, and how it manages concerns about pharmacy professionals. Nigel will also look ahead to the issues and challenges that pharmacy and pharmacy regulation will face in the future, and discuss how to prepare for those issues and challenges.